Research Themes

Research at the Cambridge Biomedical Research Centre is divided into a number of therapeutic areas described as themes with several cross cutting research themes. The core priority for the NIHR Cambridge Biomedical Research Centre is translational medicine, delivering science from the bench to the bedside.

Antimicrobial resistance

Antimicrobial resistance (AMR) is a growing problem in hospitals and other healthcare settings…Read more


Five of the top 10 causes of disease-related death in the UK are cancers. We aim to reduce the morbidity (diseased or unhealthy) and mortality (death) rates…Read more

Cardiovascular and respiratory disease

Cardiovascular and respiratory diseases are the leading causes of premature death worldwide; in the UK alone, 1 in 4 of us will die from heart disease…Read more

Dementia and neurodegenerative disorders

As the population ages, we are likely to see more and more patients developing chronic (long-lasting) degenerative brain diseases…Read more

Gastrointestinal disease

This theme aims to transform our understanding, management and treatment of major intestinal and liver diseases…Read more

Integrative genomics

The last 10 years have seen an extraordinary revolution in our ability to sequence (order) the human genome in large numbers of people…Read more

Mental health

Mental health disorders, like depression, addiction and psychosis (when you ‘lose touch’ with reality and may experience hallucinations…Read more

Metabolism, endocrinology and bone

Our research is helping to increase our understanding about metabolic, endocrine and musculoskeletal diseases…Read more


The number of people with neurological disease in the UK is rising. This is due both to advances in patient care and treatment and to the fact…Read more

Nutrition diet and lifestyle

How do dietary, nutritional and lifestyle behaviours lead to chronic (long-lasting) diseases? And how can we develop treatments or cures…Read more

Population and quantitative sciences

More than half of clinical studies fail, usually because the drug being tested simply doesn’t work very well…Read more

Transplantation and regenerative medicine

Organ transplantation is life-transforming and life-saving for hundreds of thousands of patients worldwide…Read more

Women’s health and paediatrics

The Cambridge BRC Women’s Health and paediatrics research focuses on treating and preventing health issues…Read more