The latest list of publications from the NIHR Cambridge Biomedical Research Centre with a brief summary.
If you are publishing research which has had funding and / or support from the NIHR Cambridge Biomedical Research Centre, please complete this form.View publication
Publication: PLoS Genetics
Darlay R, Ayers KL, Mells GF, Hall LS, Liu JZ, Almarri MA, et al.
3 December 2018View publication
Publication: New England Journal
Grinfeld J, Nangalia J, Baxter EJ, Wedge DC, Angelopoulos N, Cantrill R, Godfrey AL, Papaemmanuil E, Gundem G, MacLean C, Cook J, O’Neil L, O’Meara S, Teague JW, Butler AP, Massie CE, Williams N, Nice FL, Andersen CL, Hasselbalch HC, Guglielmelli P, McMullin MF, Vannucchi AM, Harrison CN, Gerstung M, Green AR, Campbell PJ.
11 October 2018View publication
Publication: Expert Review of Neurotherapeutics
Killen MJ, Giorgi-Coll S, Helmy A, Hutchinson PJ, Carpenter KL.
8 March 2019View publication
Publication: Lung Cancer
Matys T, Drury R, David S, Rassl DM, Qian W, Rintoul RC, et al. Corrigendum to
10 June 2018View publication
Barker RA, Gotz M, Parmar M.
16 May 2018View publication
5 January 2018
Publication: Neurobiology of Aging
Mak E, Padilla C, Annus T, Wilson LR, Hong YT, Fryer TD, Coles JP, Aigbirhio FI, Menon DK, Nestor PJ, Zaman SH.
August 2018View publication
Publication: Nature Communications
Park SE, Pham DT, Boinett C, Wong VK, Pak GD, Panzner U, et al.
30 November 2018View publication
Loes CA Rutten-Jacobs, Susanna C Larsson,, Rainer Malik,, Kristiina Rannikmäe, MEGASTROKE consortium, International Stroke Genetics Consortium, Cathie L Sudlow, Martin Dichgans, Hugh S Markus, professor2, Matthew Traylor
24 October 2018
Researchers investigated whether a genetic risk score for stroke is associated with actual (“incident”) stroke in a large population of British adults.
They developed a genetic risk score based on 90 gene variants known to be associated with stroke from 306,473 white men and women in the UK Biobank – a database of biological information from half a million British adults.
Participants were aged between 40 and 73 years and had no history of stroke or heart attack. Adherence to a healthy lifestyle was based on four factors: non-smoker, diet rich in fruit, vegetables and fish, not overweight or obese (body mass index less than 30), and regular physical exercise.
A high genetic risk combined with an unfavourable lifestyle profile was associated with a more than twofold increased risk of stroke compared with a low genetic risk and a favourable lifestyle. Full story hereView publication
Publication: PLoS Neglected Tropical Diseases
Britto CD, Wong VK, Dougan G, Pollard AJ.
11 October 2018View publication
Publication: American Society for Microbiology
Klemm EJ, Shakoor S, Page AJ, Qamar FN, Judge K, Saeed DK, Wong VK, Dallman TJ, Nair S, Baker S, Shaheen G, Qureshi S, Yousafzai MT, Saleem MK, Hasan Z, Dougan G, Hasan R
20 February 2018View publication
Forbester JL, Lees EA, Goulding D, Forrest S, Yeung A, Speak A, Clare S, Coomber EL, Mukhopadhyay S, Kraiczy J, Schreiber F, Lawley TD, Hancock REW, Uhlig HH, Zilbauer M, Powrie F, Dougan G.
14 September 2018View publication