Publication: Diabetes Care
Scholtens DM, Kuang A, Lowe LP, Hamilton J, Lawrence JM, Lebenthal Y, Brickman WJ, Clayton P, Ma RC, McCance D, Tam WH, Catalano PM, Linder B, Dyer AR, Lowe WL Jr, Metzger BE; HAPO Follow-Up Study Cooperative Research Group.
7 January 2019
Publication: Nature
Margherita Y. Turco, Lucy Gardner, Richard G. Kay, Russell S. Hamilton, Malwina Prater, Michael S. Hollinshead, Alasdair McWhinnie, Laura Esposito, Ridma Fernando, Helen Skelton, Frank Reimann, Fiona M. Gribble, Andrew Sharkey, Steven G. E. Marsh, Stephen O’Rahilly, Myriam Hemberger, Graham J. Burton & Ashley Moffett
28 November 2018
Summary:
During pregnancy a complex interaction between the mother and the embryo/fetus takes part to secure placental provision of nutrients to the fetus. Human models of this interaction, involving so called trophoblast invasion, had not been established, making it difficult to study this process, that results in life threatening diseases when it goes wrong.
The laboratory of Aschley Moffett, who led this research, established a new organoid model for human trophoblast/placenta development. Our contribution was LC-MS/MS showing that this model faithfully produced pregnancy related hormones.
This organoid model will be transformative for studying human placental development and for investigating trophoblast interactions with the local and systemic maternal environment.
Publication: The Lancet
Tauschmann M, Thabit H, Bally L, Allen JM, Hartnell S, Wilinska ME, Ruan Y, Sibayan J, Kollman C, Cheng P, Beck RW, Acerini CL, Evans ML, Dunger DB, Elleri D, Campbell F, Bergenstal RM, Criego A, Shah VN, Leelarathna L, Hovorka R; APCam11 Consortium.
3 October 2018
Publication: LancetThe Lancet Child & Adolescent Health
Gaccioli F, Sovio U, Cook E, Hund M, Charnock-Jones DS, Smith GCS.
August 2018
Publication: Best Practice & Research Clinical Obstetrics & Gynaecology
Smith GCS. Best Pract Res Clin Obstet Gynaecol.
May 2018
Publication: Nature
Norah M. E. Fogarty, Afshan McCarthy, Kirsten E. Snijders, Benjamin E. Powell, Nada Kubikova, Paul Blakeley, Rebecca Lea, Kay Elder, Sissy E. Wamaitha, Daesik Kim, Valdone Maciulyte, Jens Kleinjung, Jin-Soo Kim, Dagan Wells, Ludovic Vallier, Alessandro Bertero10, James M. A. Turner & Kathy K. Niakan
20 September 2017
Publication: Nature
Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, Buckwalter MS, Rowitch DH, Dawson VL, Dawson TM, Stevens B, Barres BA.
18 January 2017
Publication: Placenta
Gaccioli F, Lager S, Sovio U, Charnock-Jones DS, Smith GCS.
28 October 2016
Publication: Nat Genet
Cleaton MA, Dent CL, Howard M, Corish JA, Gutteridge I, Sovio U, Gaccioli F, Takahashi N, Bauer SR, Charnock-Jones DS, Powell TL, Smith GC, Ferguson-Smith AC, Charalambous M.
24 October 2016
The NIHR BRC: Cambridge is part of the NIHR and hosted by Cambridge University Hospitals NHS Foundation Trust in partnership with the University of Cambridge. We are at the heart of the Cambridge Biomedical Campus, Europe’s largest health research area.
NIHR Biomedical Research Centre: Cambridge
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📣 Funding opportunity: research to transform health, care and wellbeing for children and young people.
Applications are now open for PGfAR – October 2026, in partnership with @RCPCHtweets.
We’re looking for programmes that build sustainable research partnerships and bring
Early career health and care researchers can apply for funding to host and mentor students from underrepresented professions to consider a career in research.
It's an opportunity to develop a competitive funding application and experience supervising junior members of staff.
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What an amazing summer! ☀️ From county shows to festivals, our PPI team have been out and about across the region meeting members of the public to talk about health #research. Take a look at some of the places we’ve visited. @NIHRresearch #PPI
Take a look at our latest #ResearchFunding opportunities 👇
More funding and development opportunities can be found at: https://www.nihr.ac.uk/funding-opportunities
Applications closing soon⏰
Our Senior Investigator scheme will be closing on 14th September.
NIHR Senior Investigators help shape the direction of health and care research in the UK. They;
➡️ mentor early-career researchers
➡️ influence national research strategy and funding
