A maternal serum metabolite ratio predicts large for gestational age infants at term: a prospective cohort study
Publication: The Journal of Clinical Endocrinology & Metabolism
19 November 2021
Summary
Large size at birth is associated with complications in the mother and the baby. Alongside work in fetal growth restriction (FGR), researchers analysed their previously developed metabolite ratio in relation to large for gestational age (LGA) infants born at term.
They found that the metabolite ratio predictive of FGR was inversely associated with both LGA and birth weight z score as a continuous trait. These findings, obtained from the Pregnancy Outcome Prediction study, were externally validated in the Born in Bradford study.