Characterization of disease course and remission in early seropositive rheumatoid arthritis: results from the TACERA longitudinal cohort study

Publication: Therapeutic Advances in Musculoskeletal Disease

Michael Barnes, Sarah Brockbank, Ian N Bruce, Coziana Ciurtin, Andrew P. Cop, Michael R. Ehrenstein, Paul Emery, Benjamin A. Fisher, John Isaacs, Ruth Matthews, Iain B. McInnes, Hayley Noble, Ayako Wakatsuki Pedersen, Costantino Pitzalis, Karim Raza, Anthony Rowe, Gemma Simpson, Dominic Stringer, Peter C. Taylor, Brian Tom, Yujie Zhong

21 October 2021


Summary
Researchers carried out a longitudinal observational study of newly diagnosed, seropositive rheumatoid arthritis patients from 28 UK centres. Every 3 months over a total of 18 months, clinical and laboratory measures were collected. To understand the progression of the disease it was measured against the 28-joint Disease Activity Score with C-reactive protein (DAS28-CRP) and Simplified Disease Activity Index (SDAI). Researchers found that collecting biological markers early after diagnosis could help manage the disease.
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