Cardiorespiratory fitness assessment using risk-stratified exercise testing and dose-response relationships with disease outcomes

Publication: Scientific Reports

Tomas I. Gonzales, Kate Westgate, Tessa Strain, Stefanie Hollidge, Justin Jeon, Dirk L. Christensen, Jorgen Jensen, Nicholas J. Wareham & Søren Brage

28 July 2021


Summary

High cardiorespiratory fitness is associated with improved health, but exercise tests to measure fitness can be risky for some people.

Researchers developed a novel method to estimate fitness from lower-risk personalised exercise tests. The validity of the new method outperformed previous methods. The team then applied it to examine associations between fitness and health outcomes in the UK Biobank Study. Again, the new method was better than other approaches: Fitness could be estimated in more study participants, and fitness-to-health relationships were stronger. These results reinforce the importance of cardiorespiratory fitness for human health.

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