Activation of the hypothalamic–pituitary–adrenal axis by exogenous and endogenous GDF15

Publication: Proceedings of the National Academy of Sciences (PNAS)

Irene Cimino, Hanna Kim, Y. C. Loraine Tung, Kent Pedersen, Debra Rimmington, John A. Tadross,  Sara N. Kohnke, Ana Neves-Costa, André Barros, Stephanie Joaquim, Don Bennett, Audrey Melvin, Samuel M. Lockhart,  Anthony J. Rostron, Jonathan Scott, Hui Liu,  Keith Burling, Peter Barker, Menna R. Clatworthy, E-Chiang Lee,A. John Simpson, Giles S. H. Yeo, Luís F. Moita, Kendra K. Bence, Sebastian Beck Jørgensen, Anthony P. Coll, Danna M. Breen, and Stephen O’Rahilly

30 June 2021


Summary

Researchers have described a new way that the body senses damage and activates hormones in response to stressful situations – involving the protein GDF15

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