Neuroinflammation predicts disease progression in progressive supranuclear palsy

Publication: Journal of Neurology, Neurosurgery and Psychiatry

Maura Malpetti, Luca Passamonti, P Simon Jones, Duncan Street, Timothy Rittman, Timothy D Fryer, Young T Hong, Patricia Vàsquez Rodriguez,  W Richard Bevan-Jones, Franklin I Aigbirhio, John T O’Brien, James B Rowe

17 March 2021


Summary:

Progressive supranuclear palsy (PSP) causes dementia and movement disorders. Researchers show that it is associated with brain inflammation, in addition to tau protein build-up. Using a PET (Positron Emission Tomography ) brain scan they were able to map the presence of inflammation in the brain of living volunteers with PSP, who were followed up for several years.

View publication

© Copyright - NIHR Cambridge Biomedical Research Centre 2025