Validation of the new pathology staging system for progressive supranuclear palsy
Publication: Acta Neuropathologica
Mayen Briggs, Kieren Allinson, Maura Malpetti, Maria G. Spillantini, James B. Rowe, Sanne S. Kaalund
16 March 2021
Summary:
Progressive supranuclear palsy (PSP) is a neurodegenerative disorder. Researchers test the new PSP pathology staging system in an independent series of PSP, and test the potential association between pathology stage and clinical severity at death.
Researchers show that those with a higher pathology stage – more widespread pathology, at post mortem also scored higher on disease severity scales in life.