A blood-based prognostic biomarker in IBD

Publication: Gut

Daniele Biasci, James C Lee Nurulamin M Noor, Diana R Pombal, Monica Hou, Nina Lewis, Tariq Ahmad, Ailsa Hart, Miles Parkes, Eoin F McKinney, Paul A Lyons, Kenneth G C Smith

1 October 2019


Summary:

Researchers have previously described a prognostic transcriptional signature in CD8 T cells that separates patients with IBD into two phenotypically distinct subgroups, termed IBD1 and IBD2. They sought to develop a blood-based test that could identify these subgroups without cell separation, and would be suitable for clinical use in Crohn’s disease (CD) and ulcerative colitis (UC).

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