Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease

Publication: The Journal of the American Medical Association (JAMA)

Brian A. Ference, Deepak L. Bhatt, Alberico L. Catapano, Chris J. Packard, Ian Graham, Stephen Kaptoge, Thatcher B. Ference, Qi Guo, Ulrich Laufs, Christian T. Ruff, Arjen Cupido1, G. Kees Hovingh, John Danesh, Michael V. Holmes, George Davey Smith, Kausik K. Ray, Stephen J. Nicholls, Marc S. Sabatine

2 September 2019


Summary:

Most cardiovascular events can be prevented with sustained exposure to modestly lower combinations of lipoprotein cholesterol
(LDL-C) and lower systolic blood pressure (SBP), according to research led by Cambridge researchers who carried out Mendelian randomization analyses involving 438,952 participants. Read the full story here.

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